Bölüm anahatları

  • In genetic diseases, the structure of the drug molecule is a very important parameter. Depending on the nature of genetic differentiation, structural differences in the required drug molecule and variations in the molecular substitution template may change the way genes bind to the proteins they encode. Due to differences in protein behavior due to mutations in the genetic structure, it is necessary to predict individual genetic differentiation, especially diseases with genetic roots, such as cancer, diabetes and Alzheimer's disease. Because, even if the disease is the same, the drug molecule that will affect the protein mutation that changes in person is also different. This requires the treatment of the chemometrics of the medicinal chemistry methods on the genomic approach.