The genetic structure of humans can be explored in two ways, usually from their ancestors and later gained according to their lifestyle. The change of the genetic expression can also cause the proteins that function depending on the coding of the genes to change. These changes are also important differences in the treatment of diseases. For example, changes in protein structure due to differences in genetic structure in different individuals with the same disease may result in successful or unsuccessful treatment methods. The use of the same drug molecule in hypertensive patients with the same mechanism does not produce the same results in the treatment of these patients. Therefore, it is necessary to consider the treatment of individualized forms of treatment and to classify the differences in drug molecules in terms of their genomics, proteomics and chemoformative patterns in terms of Medicinal and Pharmaceutical Chemistry. The classification of the genes and the proteins they encode involves the guiding and deterministic stages of new drug design in the approach of "no disease, patient exists".
Drug molecules need to interact with a protein structure in order to be able to show their biological effects. Depending on the gene, mutated protein constructs have different affinities and activation (inhibition and / or stimulation) processes for drug molecules, so the response to treatment will be different. For this reason, medicinal chemistry is essential for the evaluation of chemoformatic and bioinformatic methods using rational molecular designs in their interactions with differentiated protein structures due to the redesign of drug molecules and genetic alterations of individuals.
To this end, this derste primarily deals with the chemoformatical importance and evaluation processes of the human genetic structure of Medisinal Kim, addressing the chemoinformatic and bioinformatic affinities, potentially addressing the therapeutic implications of molecular changes within the pharmaceutical profession's superiority in the field of drug molecules, functions are being tried to be improved.