Bölüm anahatları

  • While genomics and proteomics are involved in bioinformatics, their methodological use in new drug designs can be considered within the concept of chemoinformatics. By describing the biological effect of an organic molecule formed by the presence of common points in the storage of biological and chemical data and the use of information, ligand-protein interactions can be addressed with explanatory expressions on some models. For this, the affinity and activation levels of the proteins encoded by the genes can be reduced to levels that can be explained by both bioinformatic and chemoinformatic methods.

    By analyzing biological and genetic information, we can determine by bioinformatic and chemoinformatic methods that these molecules can undergo major transformation according to the change in electrostatic, hydrophobic and steric templates in the molecular structures of the compounds that may be the proposed drug candidates.