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Doç. Dr. Aylin Üstündağ
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◄ Doç. Dr. İlker Ateş
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Prof. Dr. Tülay Çoban
Prof. Dr. Benay Can Eke
Prof. Dr. Yalçın Duydu
Prof. Dr. Halit Sinan Süzen
Prof. Dr. Ahmet Oğuz Ada
Doç. Dr. İlker Ateş
Doç. Dr. Özge Ülker
PHA495 PHARMACEUTICAL TOXICOLOGY PRACTICE I - SCHEDULE
General information
Phase 1 reactions ethoxyresorufin-o-deethylase (erod) activity and determination of cotinine
The isolation of DNA molecule from biological material and analyses
Determination of GSTM1 and GSTT1
Determination of GSTP1 (Ala114Val) single nucleotide polymorphism
Analysis of GSTP1 (Ala114Val) restriction product
Genotoxicity tests used in the determination of chromosomal damage
Lipid peroxidation
Determination of antioxidants (DPPH,GLUTATHION)
Cytotoxicity
Teratogenesis
Determination of acute toxicity (LD50)
Determination of acute toxicity (LD50)
Doç. Dr. Özge Ülker ►
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