PHA715-Genomics and Chemoinformatics in Medicinal Chemistry-DOÇ.DR.ZÜHAL KILIÇ-KURT

Over the last two decades, several new genomics technologies have been developed in hopes of addressing the issues of target identification and lead candidate optimization. With the successful integration of these technologies into the drug discovery process, more rational approaches are emerging in target selection and clinical trial design in drug research and development studies. Knowledge of all the human genes and their functions change drug research strategy and drug discovery development processes. Within the scope of this course, the structures of nucleic acids (DNA, RNA) and proteins, which are biological molecules that are drug targets in medicinal chemistry, the concepts of genomics and proteomics and metabolomics, genomics approaches in drug design and drug molecules developed with these approaches are discussed.